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胃肠道间质瘤（GIST）是最常见的消化道间叶源性肿瘤，存在一定的恶变风险，危险度分级对制定个体化治疗方案及预后判断具有重要意义。既往主要依赖穿刺活检来进行风险评级。然而，该技术具有侵入性，可导致肿瘤破裂、出血及种植转移。此外，鉴于肿瘤的异质性，组织活检难以反映病灶全貌，在早期治疗和术后评估中存在局限性。随着医学影像技术、计算机科学和人工智能的交叉融合，采用多模态技术无创预测GIST的危险度已成为前沿研究方向。现全面梳理多模态影像学技术在无创预测GIST危险度分级中的研究现状，深入探讨当下面临的技术挑战，并展望未来的研究方向，为推进GIST精准医疗实践提供理论参考。
Abstract：Gastrointestinal stromal tumor(GIST) is the most common mesenchymal tumor of the digestive tract, carrying a certain risk of malignancy. Its risk stratiffcation is of signiffcant importance for formulating individualized treatment plans and predicting prognosis. In the past, risk assessment primarily relied on needle biopsy. However, this technique is invasive and can lead to tumor rupture, bleeding, and implantation metastasis. Furthermore, given the heterogeneity of tumors, tissue biopsy often fails to reflect the full picture of the lesion, presenting limitations in early treatment and postoperative evaluation. With the convergence of medical imaging technology, computer science, and artiffcial intelligence, the noninvasive prediction of GIST risk using multimodal techniques has become a forefront research direction. This article comprehensively reviews the current research status of multimodal imaging techniques in the non-invasive prediction of GIST risk stratiffcation, delves into the existing technical challenges, and prospects future research directions, aiming to provide a theoretical reference for advancing precision medicine practices in GIST.
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基本信息:
DOI：10.16068/j.1000-1824.2026.03.002
中图分类号:R735
引用信息:
[1]李嘉童,金光玉.多模态影像学技术无创预测胃肠道间质瘤危险度分级的现状与展望[J].延边大学医学学报,2026,49(03):5-9.DOI:10.16068/j.1000-1824.2026.03.002.
基金信息:
国家自然科学基金（编号：NO.82160329）
2026-03-28
2026-03-28